Invitrogen™ CXXC5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104329

Catalog No. PIPA5104329

Description

Antibody detects endogenous levels of total CXXC5.

CXXC5 is zinc finger protein closely related to the DVL1-binding protein CXXC4 (also known as Idax), and like CXXC4 is thought to modulate the Wnt signaling pathway during development. CXXC5 is upregulated in neural stem cells upon BMP4 stimulation, leading to decreased levels of the Wnt-signaling target AXIN2 and facilitated the response of the stem cells to Wnt3a. Recent reports suggest CXXC5 transcription is activated by the Wilms tumor 1 (WT1) transcription factor, and together are involved in the WNT/beta-catenin pathway and play a role in embryonic kidney development.

Specifications

• Antigen: CXXC5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CXXC5
• Gene Alias: 4930415K17Rik; CF5; CXXC finger 5; CXXC finger 5 protein; CXXC finger protein 5; Cxxc5; CXXC-type zinc finger protein 5; HSPC195; Putative MAPK-activating protein PM08; putative NF-kappa-B-activating protein 102; Retinoid-inducible nuclear factor; RINF; TCCCIA00297; WID; WT1-induced Inhibitor of Dishevelled
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 291670, 51523, 67393
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q5XIQ3, Q7LFL8, Q91WA4
• Gene Symbols: CXXC5
• Immunogen: A synthesized peptide derived from human CXXC5(Accession Q7LFL8), corresponding to amino acid residues P46-M96.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov