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Invitrogen™ CYBA Monoclonal Antibody (44.1)
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Catalog No. PIMA518049
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100 μL
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Catalog No. Quantity
PIMA518049 100 μL
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Catalog No. PIMA518049 Supplier Invitrogen™ Supplier No. MA518049
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Description

Mouse Monoclonal Antibody

This antibody is specific for human Cytochrome b245 light chain aa 29-33 (TAGRF) and 183-188 (PQVNPI). The immunogen was prepared using partially purified human neutrophil flavocytochrome b (heparin Ultrogel/lectin affinity purification in Triton X-100). This target has a predicted molecular weight of 21 kDa.

Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYBA
Applications Western Blot
Classification Monoclonal
Clone 44.1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene CYBA
Gene Accession No. P13498
Gene Alias b558; CYBA; cytochrome b light chain; cytochrome b(558) alpha chain; cytochrome b(558) alpha-subunit; cytochrome b, alpha polypeptide; cytochrome b-245 alpha chain; cytochrome b-245 light chain; cytochrome b-245, alpha polypeptide; cytochrome b558 alpha-subunit; cytochrome b558 subunit alpha; cytochrome beta-558; flavocytochrome b-558 alpha polypeptide; neutrophil cytochrome b 22 kDa polypeptide; nmf333; p22 phagocyte B-cytochrome; p22 phox; p22phox; p22-PHOX; superoxide-generating NADPH oxidase light chain subunit
Gene Symbols CYBA
Host Species Mouse
Immunogen Partially Purified human neutrophil flavocytochrome b.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1535
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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