Invitrogen™ CYBA Monoclonal Antibody (CS9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA518047

Catalog No. PIMA518047

Description

This antibody is specific for human Cytochrome b245 light chain (aa 165-169, KKPSE). This target has a predicted molecular weight of 21 kDa.

Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.

Specifications

• Antigen: CYBA
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P13498
• Gene Symbols: CYBA
• Immunogen: Partially purified human neutrophil flavocytochrome b (heparin Ultrogellectin affinity purification in octyl glucoside).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: CS9
• Conjugate: Unconjugated
• Gene: CYBA
• Gene Alias: b558; CYBA; cytochrome b light chain; cytochrome b(558) alpha chain; cytochrome b(558) alpha-subunit; cytochrome b, alpha polypeptide; cytochrome b-245 alpha chain; cytochrome b-245 light chain; cytochrome b-245, alpha polypeptide; cytochrome b558 alpha-subunit; cytochrome b558 subunit alpha; cytochrome beta-558; flavocytochrome b-558 alpha polypeptide; neutrophil cytochrome b 22 kDa polypeptide; nmf333; p22 phagocyte B-cytochrome; p22 phox; p22phox; p22-PHOX; superoxide-generating NADPH oxidase light chain subunit
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 1535
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid