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Invitrogen™ Cyclin A2 Monoclonal Antibody (E23.1)
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Catalog No. PIMA1154
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100 μg
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Catalog No. Quantity
PIMA1154 100 μg
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Catalog No. PIMA1154 Supplier Invitrogen™ Supplier No. MA1154
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Description

Mouse Monoclonal Antibody

MA1-154 detects Cyclin A in mammalian samples and has been successfully used in Immunohistochemistry (Frozen and Paraffin), Immunofluorescence, Immunoprecipitation and Western Blot procedures. Immunoprecipitation and Western Blot analysis with MA1-154 show the accumulation of a prominent band at ~50 kDa in camptothecin and hydroxyurea treated cells. In Immunofluorescence applications, MA1-154 shows nuclear translocation of Cyclin A in G2/M arrested cells as a result of camptothecin treatment.

Cyclins are regulatory subunits of the cyclin-dependent kinases (cdks) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdks. These cyclin / cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S phase and passage through G2-phase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cyclin A2
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone E23.1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
Gene CCNA2
Gene Accession No. P20248, P30274, P51943
Gene Alias AA408589; Ccn1; Ccn-1; CCNA; CCNA2; ccna2.S; Cyca; CycA2; Cyclin A; cyclin A2; Cyclin A2 (Cyclin A); cyclin A2 S homeolog; Cyclin A-3; cyclin-A; Cyclin-A2; XELAEV_18009326mg
Gene Symbols CCNA2
Host Species Mouse
Immunogen Bovine Cyclin A fusion protein.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114494, 12428, 281667, 890
Target Species Human, Mouse, Rat, Monkey, Bovine
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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