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Invitrogen™ Cyclin B3 Polyclonal Antibody
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Catalog No. PIPA599827
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100 μL
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PIPA599827 100 μL
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Catalog No. PIPA599827 Supplier Invitrogen™ Supplier No. PA599827
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CCNB3.

Cell proliferation is controlled at specific stages of the cell cycle by distinct protein kinase complexes. These complexes consist of a catalytic subunit associating with a specific regulatory subunit to form the active kinase. The cyclins, which include cyclin A, B, C, D, E, F, G, H, I, K, L, T and their related proteins, including Dbf4, comprise the regulatory subunits of these kinase complexes. The controlled activation of the kinase complexes at various intervals of the cell cycle is regulated by the availability of the cyclins to the catalytic subunit. Unlike the catalytic subunit, which is expressed continually, the expression and stability of the regulatory subunit fluctuates depending on the stage of the cell cycle, thereby regulating kinase activity. Cyclin B3, also known as CCNB3 or CYCB3, is a 1,395 amino acid nuclear protein that belongs to the cyclin family of regulatory proteins. Expressed in testis with lower expression in a variety of other tissues, cyclin B3 is thought to be required for early meiotic prophase I, playing an important role in the meiotic cell cycle. Three isoforms of cyclin B3 exist due to alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cyclin B3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CCNB3
Gene Accession No. Q8WWL7
Gene Alias CCNB3; CYCB3; cyclin B3; CyclinB3; G2/mitotic-specific cyclin-B3; Protein Ccnb3; RGD1564367
Gene Symbols CCNB3
Host Species Rabbit
Immunogen A synthesized peptide derived from human CCNB3(Accession Q8WWL7), corresponding to amino acid residues P6-A56.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 85417
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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