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Invitrogen™ Cyclin C Polyclonal Antibody
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Catalog No. PIPA514981
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400 μL
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PIPA514981 400 μL
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Catalog No. PIPA514981 Supplier Invitrogen™ Supplier No. PA514981
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Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine, chicken, mouse, rat and Xenopus based on sequence homology.

Cyclin C was originally identified by a genetic screen for human and Drosophila cDNAs that complement a triple knock out of the CLN genes in Saccharomyces cerevisiae. Cyclin C is a nuclear protein present in a multiprotein complex. It interacts both in vitro and in vivo with cdk 8, a novel protein kinase of the cdk family. It is suggested that cyclin C and cdk 8 control RNA polymerase II function. Human cdk 8 cyclin C might be functionally associated with the mammalian transcription apparatus, perhaps involved in relaying growth regulatory signals.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cyclin C
Applications Western Blot
Classification Polyclonal
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene CCNC
Gene Accession No. P24863
Gene Alias AI451004; AU020987; CCNC; CG1C; CycC; cyclin C; cyclin-C; dJ199J3.4 (cyclin C); hSRB11; SRB11 homolog
Gene Symbols CCNC
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 221-249 amino acids from the C-terminal region of human Cyclin C (CCNC).
Purification Method Ammonium sulfate precipitation, Size-exclusion - Dialysis
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 892
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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