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  6. Epredia™ Lab Vision™ Cyclin E Ab-5, Mouse Monoclonal Antibody

Epredia™ Lab Vision™ Cyclin E Ab-5, Mouse Monoclonal Antibody

Catalog No. MS1060S0 Shop All Epredia Products
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500 μL
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7 mL
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Catalog No. Quantity Form
MS1060S0 100 μL Concentrated
MS1060S1 500 μL Concentrated
MS1060S 1 mL Concentrated
MS1060R1 1 mL Prediluted
MS1060R7 7 mL Prediluted
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Catalog No. MS1060S0 Supplier Epredia™ Supplier No. MS1060S0

Description

Obtain accurate, reproducible results in immunohistochemistry and immunoprecipitation experiments with Epredia™ Cyclin E Ab-5, Mouse Monoclonal Antibody.

Cyclin E is a regulatory subunit of cdk-2 and controls G1/S transition during the mammalian cell cycle. Multiple isoforms of cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post-transcriptional regulation of cyclin E. In vitro analyses indicated that these truncated variant isoforms of cyclin E are able to phosphorylate histone H1. Alterations in cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

Host Species: Mouse

Clone: 13A3

Isotype: IgG2a/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human cyclin E protein

Molecular Weight: Doublet of 50 kDa and a single band of 42 kDa

Positive Control: SKBR3 and LS174T cells; Breast CA or placenta

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Immunoprecipitation (Native and Denatured)

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen Cyclin E Ab-5
Applications Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Monoclonal
Clone 13A3
Conjugate Unconjugated
Host Species Mouse
Immunogen Recombinant human cyclin E protein
Purification Method SKBR3 and LS174T cells, breast CA or placenta
Quantity 100 μL
Regulatory Status RUO
Research Discipline Cell Cycle
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG2a κ
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