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Cyclin E1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501727261 Shop All Proteintech Group Inc Products
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50-172-7261 150 μL
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Catalog No. 50-172-7261 Supplier Proteintech Group Inc Supplier No. 115541AP150UL
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Description

Rabbit Polyclonal Antibody

Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

Specifications

Antigen Cyclin E1
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 0.31 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene CCNE1
Gene Accession No. P24864, Q61457
Gene Alias CCNE, CCNE1, cyclin E1, G1/S specific cyclin E1
Gene Symbols CCNE1
Host Species Rabbit
Immunogen Cyclin E1 Fusion Protein Ag2110
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12447, 898
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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