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Invitrogen™ Cyclin G1 Monoclonal Antibody (1E3)
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Catalog No. PIMA518550
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100 μg
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Catalog No. Quantity
PIMA518550 100 μg
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Catalog No. PIMA518550 Supplier Invitrogen™ Supplier No. MA518550
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Description

Mouse Monoclonal Antibody

Peptide Sequence: MIEVLTTTDS QKLLHQLNAL LEQESRCQPK VCGLRLIESA HDNGLRMTAR LRDFEVKDLL SLTQFFGFDT ETFSLAVNLL DRFLSKMKVQ PKHLGCVGLS CFYLAVKSIE.

Cyclins are the regulatory subunits of Cdc2 p34 and related cyclin-dependent kinases (Cdks) which play critical roles in the control of cell cycle progression. The catalytic subunit for cyclin A and B is Cdc2 p34 kinase. The Cdc2- cyclin B complex controls the G2 to M transition whereas Cdc2-cyclin A regulates S phase progression. The G1 to S transition, however, appears to be controlled by the G1 cyclins. Cyclin D1 accumulates during G1 and associates with Cdk2, Cdk4 and Cdk5. Cyclin E and Cdk2 interact during the G1 to S transition. Cyclin G contains a typical N terminal cyclin box and a carboxy terminal domain sequence homologous to the tyrosine phosphorylation site of the epidermal growth factor receptor. Cyclin G expression is induced within 3 hours after growth stimulation and remains elevated with no apparent cell cycle dependency. Cyclin G2 shares 53% amino acid sequence identity with cyclin G1. Peak expression of cyclin G2 is seen in late S phase, as opposed to cyclin G1 expression, which is constitutive.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cyclin G1
Applications ELISA
Classification Monoclonal
Clone 1E3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene Ccng1
Gene Accession No. P51959
Gene Alias AI314029; CCNG; CCNG1; CYCG; CYCG1; cyclin G1; cyclin-G; Cyclin-G1
Gene Symbols Ccng1
Host Species Mouse
Immunogen CCNG1 (AAH00196, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 900
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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