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Invitrogen™ Cyclin H Monoclonal Antibody (33TF2-2D4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA3025

Catalog No. MA3025


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Description

Description

MA3-025 has been used successfully in Western blotting, Immunoprecipitation and Immunofluorescence applications to detect Cyclin H in human samples.

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Cyclin H
Monoclonal
Conc. Not Determined
ascites with 0.05% sodium azide
P51946
CCNH
Synthetic peptide (KKRKGYEDDDYVSKKSKHEE) corresponding to aa 292-311 (C-terminal region) of human cyclin H.
RUO
902
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Immunoprecipitation, Western Blot, Immunocytochemistry
33TF2-2D4
Unconjugated
CCNH
6330408H09Rik; AI661354; AV102684; AW538719; CAK; CAK complex subunit; Ccnh; CDK-activating kinase complex subunit; CycH; cyclin H; cyclin-dependent kinase-activating kinase complex subunit; cyclin-H; MO15-associated protein; OTTHUMP00000222395; OTTHUMP00000222396; p34; p37
Mouse
50 μL
Primary
Human
Antibody
IgG1 κ
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