Invitrogen™ Cyclin H Monoclonal Antibody (33TF2-2D4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA3025

Catalog No. MA3025

Description

MA3-025 has been used successfully in Western blotting, Immunoprecipitation and Immunofluorescence applications to detect Cyclin H in human samples.

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery.

Specifications

• Antigen: Cyclin H
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.05% sodium azide
• Gene Accession No.: P51946
• Gene Symbols: CCNH
• Immunogen: Synthetic peptide (KKRKGYEDDDYVSKKSKHEE) corresponding to aa 292-311 (C-terminal region) of human cyclin H.
• Regulatory Status: RUO
• Gene ID (Entrez): 902
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 33TF2-2D4
• Conjugate: Unconjugated
• Gene: CCNH
• Gene Alias: 6330408H09Rik; AI661354; AV102684; AW538719; CAK; CAK complex subunit; Ccnh; CDK-activating kinase complex subunit; CycH; cyclin H; cyclin-dependent kinase-activating kinase complex subunit; cyclin-H; MO15-associated protein; OTTHUMP00000222395; OTTHUMP00000222396; p34; p37
• Host Species: Mouse
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov