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Invitrogen™ Cyclin H Recombinant Rabbit Monoclonal Antibody (3N5S3)
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Catalog No. PIMA535437
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100 μL
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PIMA535437 100 μL
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Catalog No. PIMA535437 Supplier Invitrogen™ Supplier No. MA535437
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: AGITMESYLS ESLMLKENRT CLSQLLDIMK SMRNLVKKYE PPRSEEVAVL KQKLERCHSA ELALNVITKK RKGYEDDDYV SKKSKHEEEE WTDDDLVESL.

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cyclin H
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 3N5S3
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CCNH
Gene Accession No. P51946, Q61458
Gene Alias 6330408H09Rik; AI661354; AV102684; AW538719; CAK; CAK complex subunit; Ccnh; CDK-activating kinase complex subunit; CycH; cyclin H; cyclin-dependent kinase-activating kinase complex subunit; cyclin-H; MO15-associated protein; OTTHUMP00000222395; OTTHUMP00000222396; p34; p37
Gene Symbols CCNH
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 224-323 of human Cyclin H (P51946).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 66671, 902
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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