Cyclin H Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-6536	Proteintech Group Inc 107181AP150UL	150 μL

Description

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery.

Specifications

• Antigen: Cyclin H
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: P51946, Q61458, Q9R1A0
• Gene ID (Entrez): 66671, 84389, 902
• Immunogen: Cyclin H Fusion Protein Ag1088
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: CCNH

• Concentration: 0.19 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: CAK, CCNH, cyclin H, MO15 associated protein, p34, p37
• Gene Symbols: CCNH
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody