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Invitrogen™ Cyclin L1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA540668

Catalog No. PIPA540668


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Description

Description

Peptide sequence: TTTTTTGGIL IGDRLYSEVS LTIDHSLIPE ERLSPTPSMQ DGLDLPSETD Sequence homology: Cow: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%.

FUS/TLS was originally described as fused in Sarcoma is actually related to a number of different cellular processes and correlated to several diseases. FUS binds DNA as a single or double strand, and acts as a site for transcription factors to recognize. Since FUS is well-documented to be involved in liposarcoma, lipoma and leukaemia, it is believed that when its normal housekeeping functions related to transcription are disrupted, normal cells become cancerous. Interestingly, FUS is also associated with the fatal neuron disorder amyotrophic lateral sclerosis; interruption of its normal RNA-binding functions leads to incorrect cellular localization and leads to pathologies of the neuron. Thus, FUS regulation of cellular functions is a critical component of maintenance of healthy cells.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Cyclin L1
Polyclonal
Unconjugated
Ccnl1
2610030E23Rik; ANIA6A; ania-6a; AU018493; BM-001; Ccn1; Ccnl; CCNL1; Cyclin Ania-6a; cyclin L ania-6a; cyclin L gamma; cyclin L1; cyclin-L; Cyclin-L1; LOW QUALITY PROTEIN: cyclin-L1; PRO1073; UNQ530/PRO1073
Rabbit
Protein A
RUO
57018
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Western Blot
1 mg/mL
PBS with 2% sucrose and 0.09% sodium azide
Q9UK58
Ccnl1
Synthetic peptide directed towards the N-terminal of human CCNL1 (aa 32-81).
100 μL
Primary
Human
Antibody
IgG
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