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Invitrogen™ Cyclin L1 Polyclonal Antibody
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Catalog No. PIPA584358
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100 μL
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PIPA584358 100 μL
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Catalog No. PIPA584358 Supplier Invitrogen™ Supplier No. PA584358
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SKPSSPREVK AEEKSPISIN VKTVKKEPED RQQASKSPYN GVRKDSKRSR NSRS Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 98%.

FUS/TLS was originally described as fused in Sarcoma is actually related to a number of different cellular processes and correlated to several diseases. FUS binds DNA as a single or double strand, and acts as a site for transcription factors to recognize. Since FUS is well-documented to be involved in liposarcoma, lipoma and leukaemia, it is believed that when its normal housekeeping functions related to transcription are disrupted, normal cells become cancerous. Interestingly, FUS is also associated with the fatal neuron disorder amyotrophic lateral sclerosis; interruption of its normal RNA-binding functions leads to incorrect cellular localization and leads to pathologies of the neuron. Thus, FUS regulation of cellular functions is a critical component of maintenance of healthy cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cyclin L1
Applications ChIP Assay, Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Ccnl1
Gene Accession No. Q9UK58
Gene Alias 2610030E23Rik; ANIA6A; ania-6a; AU018493; BM-001; Ccn1; Ccnl; CCNL1; Cyclin Ania-6a; cyclin L ania-6a; cyclin L gamma; cyclin L1; cyclin-L; Cyclin-L1; LOW QUALITY PROTEIN: cyclin-L1; PRO1073; UNQ530/PRO1073
Gene Symbols Ccnl1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CCNL1. Recombinant protein control fragment (Product #RP-105087).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57018
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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