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Invitrogen™ Cyclin T1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA582177
Description
Immunogen sequence: KTSEQTILNM ISQSSSDTTI AGLMSMSTST TSAVPSLPVS EESSSNLTSV EMLPGKRWLS SQPSFKLEPT QGHRTSENLA LTGVDHSLPQ DGSNAFISQK QNSKSVPSAK VSLKEYRAKH AEELAAQKRQ LEN.
This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants.
Specifications
Cyclin T1 | |
Polyclonal | |
Unconjugated | |
Ccnt1 | |
2810478G24Rik; AI115585; CCNT; CCNT1; CDK9-associated C-type protein; cyclin C-related protein; cyclin T1; cyclin T1b; cyclin-T; cyclin-T1; CycT1; HIVE1; human immunodeficiency virus type 1 (HIV-1) expression (elevated) 1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
12455, 315291, 904 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
O60563, Q9QWV9 | |
Ccnt1 | |
Recombinant protein corresponding to Human CCNT1. Recombinant protein control fragment (Product #RP-102511). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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