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Cyclooxygenase 1 Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss
SDP

Catalog No. 501980370
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50-198-0370 100 μL
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Catalog No. 50-198-0370 Supplier Bioss Supplier No. BS0582R
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Description

Rabbit Polyclonal Antibody

PTGS1 (COX1, Cyclooxygenase 1) is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.

Specifications

Antigen Cyclooxygenase 1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene PTGS1
Gene Accession No. P22437, P23219, Q63921
Gene Alias COX1; Cox-1; COX3; Cox-3; cyclooxygenase 3; cyclooxygenase precursor (EC 1.14.99.1); Cyclooxygenase-1; P PGG/HS; PCOX1; PES-1; PGG/HS; PGH synthase 1; Pghs1; PGHS-1; PHS 1; PHS1; prostaglandin endoperoxide synthase; Prostaglandin G/H synthase 1; prostaglandin G/H synthase and cyclooxygenase; prostaglandin G/H synthase precursor (EC 1.14.99.1); Prostaglandin H2 synthase 1; Prostaglandin-endoperoxide synthase 1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); PTGHS; PTGS1; unnamed protein product
Gene Symbols PTGS1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from rat Cyclooxygenase 1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19224, 24693, 5742
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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