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Tocris Bioscience™ Cyclopamine
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Catalog No. 16231
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16-231 1 mg
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Catalog No. 16-231 Supplier Tocris Bioscience™ Supplier No. 1623/1
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Description

Inhibitor of Hedgehog (Hh) signaling

Inhibitor of hedgehog (Hh) signaling, likely via direct inhibition of Smoothened, the accessory protein to the putative Hh receptor Patched. Anticancer and teratogenic in vivo. Depletes stem-like cancer cells in glioblastoma and blocks tumor engraftment. Can also be used to induce differentiation of human embryonic stem cells (hESCs) into hormone-expressing endocrine cells.

Chemical Identifiers

CAS 4449-51-8
Molecular Formula C27H41NO2

Specifications

Quantity 1 mg
Formula Weight 411.63
Purity >97%
Molecular Weight (g/mol) 411.63
Chemical Name or Material Cyclopamine

Safety and Handling

Recommended Storage Desiccate at -20°C
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