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Invitrogen™ CYFIP1 Recombinant Rabbit Monoclonal Antibody (JE64-11)
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Catalog No. PIMA544713
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100 μL
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PIMA544713 100 μL
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Catalog No. PIMA544713 Supplier Invitrogen™ Supplier No. MA544713
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Description

Rabbit Recombinant Monoclonal Antibody

CYFIP1 Recombinant Monoclonal Antibody for IHC (P), Western Blot

Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA. Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYFIP1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone JE64-11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% glycerol, 0.05% BSA and 0.05% sodium azide, pH 7.4
Gene Cyfip1
Gene Accession No. Q7L576, Q7TMB8
Gene Alias CY; CYFIP; cyfip1; cyfip1 protein; cytoplasmic FMR1 interacting protein 1; cytoplasmic FMR1-interacting protein 1; Cytoplasmic FMR1-interacting protein 1 homolog; cytoplasmic FMRP interacting protein 1; E030028J09Rik; fb15a06; FLJ45151; FMR1-interacting protein 1; KIAA0068; l(7)1Rl; l71Rl; l7Rl1; LOW QUALITY PROTEIN: cytoplasmic FMR1-interacting protein 1; mKIAA0068; P140sra1; p140sra-1; pl-1; selective hybridizing clone; Shyc; Specifically Rac1-associated protein 1; Sra1; Sra-1; Unknown (protein for IMAGE:7152255); wu:fb15a06
Gene Symbols Cyfip1
Host Species Rabbit
Immunogen Synthetic peptide within human CYFIP1 aa 51-100/1,253.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20430, 23191, 308666
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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