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Invitrogen™ CYP11B2 Polyclonal Antibody
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Catalog No. PIPA599805
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PIPA599805 100 μL
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Catalog No. PIPA599805 Supplier Invitrogen™ Supplier No. PA599805
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Cytochrome P450 11B2.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP11B2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CYP11B2
Gene Accession No. P15539, P19099, P30099
Gene Alias ALDOS; Aldosterone synthase; aldosterone-synthesizing enzyme; Corticosterone 18-monooxygenase, CYP11B2; Cp45as; Cpn2; Cyp11b; CYP11B2; Cyp11b-2; Cyp11b3; CYP11BL; CYPXIB2; CYPXIB3; cytochrome P450 11B2, mitochondrial; cytochrome P450 11B3, mitochondrial; cytochrome P450 family 11 subfamily B member 2; Cytochrome P450 subfamily XIB polypeptide 2 (aldosterone synthase); cytochrome P450, family 11, subfamily b, polypeptide 2; cytochrome P450, subfamily 11B, polypeptide 2; cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2; Cytochrome P450, subfamily XIB, polypeptide 2 (aldosterone synthase); cytochrome P-450Aldo; cytochrome P450-Aldo-1; cytochrome P450-Aldo-2; cytochrome P450C11; Cytochrome P-450C18; mitochondrial cytochrome P450, family 11, subfamily B, polypeptide 2; P450aldo; P450-Aldo-1; P450-Aldo-2; P450C 18; P-450C 18; P450C18; P-450C18; RNCP45AS; steroid 11-beta/18-hydroxylase; steroid 11-beta-hydroxylase; Steroid 11-beta-hydroxylase, CYP11B2; steroid 11-beta-monooxygenase; Steroid 18-hydroxylase; steroid 18-hydroxylase, aldosterone synthase, P450C18, P450aldo; steroid-11-beta-hydroxylase
Gene Symbols CYP11B2
Host Species Rabbit
Immunogen A synthesized peptide derived from human CYP11B2(Accession P19099), corresponding to amino acid residues M309-T359.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13072, 1585, 24294
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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