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CYP19A1 Mouse anti-Human, Clone: H4, Abnova™

Catalog No. 89934033 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-934-033 100 μL
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Catalog No. 89-934-033 Supplier Abnova Corporation Supplier No. MAB12697

Description

Mouse monoclonal antibody raised against human CYP19A1.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq]

Specifications

Antigen CYP19A1
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Monoclonal
Clone H4
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against human CYP19A1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) Western Blot (1:250) The optimal working dilution should be determined by the end user.
Formulation In tissue culture supernatant (0.09% sodium azide).
Gene Alias ARO/ARO1/CPV1/CYAR/CYP19/MGC104309/P-450AROM
Gene Symbols CYP19A1
Host Species Mouse
Immunogen A synthetic peptide corresponding to amino acids 376-390 of human CYP19A1.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1588
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG2a
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