Invitrogen™ CYP1A1/CYP1A2 Polyclonal Antibody

Catalog No.	Quantity
PIPA5101307	100 μL

Catalog No. PIPA5101307 Supplier Invitrogen™ Supplier No. PA5101307

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Cytochrome P450 1A1/2.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

Specifications

• Antigen: CYP1A1/CYP1A2
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.4
• Gene: CYP1A2
• Gene Accession No.: P00184, P00185, P00186, P04798, P04799, P05177
• Gene Alias: AHH; AHRR; aromatic compound inducible; aryl hydrocarbon hydroxylase; cholesterol 25-hydroxylase; CP11; CP12; CYP1; Cyp1a1; Cyp1a-1; CYP1A2; Cyp1a-2; Cyp45c; Cypc45c; CYPD45; CYPIA1; CYPIA2; Cytochrome P(3)450; cytochrome P1-450; cytochrome P1-450, dioxin-inducible; Cytochrome P3 450; cytochrome P-448; cytochrome P450 1A1; Cytochrome P450 1A2; cytochrome P450 4; cytochrome P450 family 1 subfamily A member 1; cytochrome P450 family 1 subfamily A member 2; cytochrome P450 family 1 subfamily a polypeptide 1; cytochrome P450 family 1 subfamily a polypeptide 2; cytochrome P450 form 6; cytochrome P450 subfamily I (aromatic compound-inducible) member A1 (C6 form c) (C6 form c); Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d); cytochrome P450 subfamily I, polypeptide 1; cytochrome P450, 1a1; cytochrome P450, 1a1, aromatic compound inducible; cytochrome P450, 1a2; cytochrome P450, 1a2, aromatic compound inducible; cytochrome P450, family 1, subfamily a, polypeptide 1; cytochrome P450, family 1, subfamily a, polypeptide 2; cytochrome P450, subfamily I (aromatic compound-inducible), member A1 (C6, form c) (C6, form c); cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d); cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1; cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2; cytochrome P450-C; Cytochrome P-450d; Cytochrome P450-D; Cytochrome P450MT2; Cytochrome P450MT2A; Cytochrome P450MT2B; cytochrome P450-P1; Cytochrome P450-P2; cytochrome P450-P3; dioxin-inducible; dioxin-inducible P3-450; flavoprotein-linked monooxygenase; Hydroperoxy icosatetraenoate dehydratase; microsomal monooxygenase; P1-450; P3-450; P-448; P450 form 4; P450(PA); P450-1; P450-3; P450-C; P-450d; P450-D; P450DX; P450form6; P-450MC; P450MT2; RATCYPD45; xenobiotic monooxygenase
• Gene Symbols: CYP1A1, CYP1A2
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human CYP1A1(Accession P04798), corresponding to amino acid residues I78-G128.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 13076, 13077, 1543, 1544, 24296, 24297
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov