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Invitrogen™ CYP1A1 Polyclonal Antibody
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Catalog No. PIPA5142819
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100 μg
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PIPA5142819 100 μg
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Catalog No. PIPA5142819 Supplier Invitrogen™ Supplier No. PA5142819
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Description

Goat Polyclonal Antibody

Additional Information: This antibody is not expected to cross-react with the similar P450 1A2. This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP1A1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene CYP1A1
Gene Accession No. P00184, P00185, P04798
Gene Alias AHH; AHRR; aromatic compound inducible; aryl hydrocarbon hydroxylase; CP11; CYP; CYP1; Cyp1a1; Cyp1a-1; Cyp1a2; Cyp45c; Cypc45c; CYPIA1; cytochrome P1-450; cytochrome P1-450, dioxin-inducible; cytochrome P450 1A1; cytochrome P450 family 1 subfamily A member 1; cytochrome P450 family 1 subfamily a polypeptide 2; cytochrome P450 form 6; cytochrome P450 subfamily I (aromatic compound-inducible) member A1 (C6 form c) (C6 form c); cytochrome P450 subfamily I, polypeptide 1; cytochrome P450, 1a1; cytochrome P450, 1a1, aromatic compound inducible; cytochrome P450, family 1, subfamily a, polypeptide 1; cytochrome P450, subfamily I (aromatic compound-inducible), member A1 (C6, form c) (C6, form c); cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1; cytochrome P450-C; cytochrome P450MT2; Cytochrome P450MT2A; Cytochrome P450MT2B; Cytochrome P450-P1; dioxin-inducible; flavoprotein-linked monooxygenase; Hydroperoxy icosatetraenoate dehydratase; microsomal monooxygenase; P1-450; P450; P450 form 6; P450-1; P450-C; P450DX; P450form6; P-450MC; P450MT2; P450-P1; xenobiotic monooxygenase
Gene Symbols CYP1A1
Host Species Goat
Immunogen Peptide with sequence C-QDRKLDENANVQLSD (aa 294-308).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13076, 1543, 24296
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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