CYP1A2 Monoclonal Antibody (OTI1H3), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA501154

Catalog No. 50-167-2297

Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme′s endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3′ untranslated region.

Specifications

• Antigen: CYP1A2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P05177
• Gene Symbols: CYP1A2
• Immunogen: Full length human recombit protein of human CYP1A2 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1H3
• Conjugate: Unconjugated
• Gene: CYP1A2
• Gene Alias: CP12, CYPIA2, P3-450, P450(PA)
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1544
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid