CYP1A2 Mouse anti-Human, Clone: OTI6E2, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF501155

Catalog No. 50-166-0189

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme′s endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3′ untranslated region.

Specifications

• Antigen: CYP1A2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: CYP1A2
• Gene Alias: CP12, CYPIA2, P3-450, P450(PA)
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1544
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI6E2
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P05177
• Gene Symbols: CYP1A2
• Immunogen: Full length human recombit protein of human CYP1A2 produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a