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Invitrogen™ CYP1B1 Polyclonal Antibody
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Catalog No. PIPA528040
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100 μL
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PIPA528040 100 μL
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Catalog No. PIPA528040 Supplier Invitrogen™ Supplier No. PA528040
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, mouse lung. Predicted reactivity: Mouse (84%), Rat (84%), Dog (82%), Rhesus Monkey (94%), Bovine (82%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CYP1B1 is a 543 amino acid intracellular protein localized to the endoplasmic reticulum. It belongs to the cytochrome P450 super family of enzymes which are monooxygenases and it catalyzes many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol and is also involved in the metabolism of substances active in the eye growth and differentiation and hence plays a putative role in ocular development. Mutated proteins are known to cause primary congenital glaucoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP1B1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.63 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Cyp1b1
Gene Accession No. Q16678, Q64429
Gene Alias aryl hydrocarbon hydroxylase; benz[a]anthracene inducible; CP1B; CYP1B; CYP1B1; Cyp1-b1; CYPIB1; cytochrome P450 1B; cytochrome P450 1B1; cytochrome P450 family 1 subfamily B member 1; cytochrome P450, 1b1, benz[a]anthracene inducible; cytochrome P450, family 1, subfamily B, polypeptide 1; cytochrome P450, subfamily 1B, polypeptide 1; cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile); cytochrome P4501B; cytochrome P450CMEF; Cytochrome P450EF; cytochrome P450RAP; flavoprotein-linked monooxygenase; GLC3A; Hydroperoxy icosatetraenoate dehydratase; microsomal monooxygenase; P4501B1; P450RAP; xenobiotic monooxygenase; zgc:136223
Gene Symbols Cyp1b1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human CYP1B1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13078, 1545
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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