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CYP1B1 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA519619
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100 μg
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Catalog No. Quantity
PIPA519619 100 μg
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Catalog No. PIPA519619 Supplier Thermo Scientific Supplier No. PA519619

Description

Rabbit Polyclonal Antibody

Heat mediated antigen retrieval recommended prior to tissue staining.

CYP1B1 is a 543 amino acid intracellular protein localized to the endoplasmic reticulum. It belongs to the cytochrome P450 super family of enzymes which are monooxygenases and it catalyzes many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol and is also involved in the metabolism of substances active in the eye growth and differentiation and hence plays a putative role in ocular development. Mutated proteins are known to cause primary congenital glaucoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP1B1
Applications Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with <1mg/mL BSA and 0.02% sodium azide
Gene Cyp1b1
Gene Accession No. Q16678
Gene Alias aryl hydrocarbon hydroxylase; benz[a]anthracene inducible; CP1B; CYP1B; CYP1B1; Cyp1-b1; CYPIB1; cytochrome P450 1B; cytochrome P450 1B1; cytochrome P450 family 1 subfamily B member 1; cytochrome P450, 1b1, benz[a]anthracene inducible; cytochrome P450, family 1, subfamily B, polypeptide 1; cytochrome P450, subfamily 1B, polypeptide 1; cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile); cytochrome P4501B; cytochrome P450CMEF; Cytochrome P450EF; cytochrome P450RAP; flavoprotein-linked monooxygenase; GLC3A; Hydroperoxy icosatetraenoate dehydratase; microsomal monooxygenase; P4501B1; P450RAP; xenobiotic monooxygenase; zgc:136223
Gene Symbols Cyp1b1
Host Species Rabbit
Immunogen Synthetic peptide conjugated to KLH derived from within residues 450 to the C-terminus of Human CYP1B1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1545
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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