Invitrogen™ CYP24A1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115083

Catalog No. PIPA5115083

Description

Antibody detects endogenous levels of total Cytochrome P450 24A1.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: CYP24A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cyp24a1
• Gene Alias: 1,25-@dihydroxyvitamin D3 24-hydroxylase; 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; 24-OHase; 24R-Ohase; 25-hydroxyvitamin D-24-hydroxylase; 25-hydroxyvitamin D3 24-hydroxylase; 25-hydroxyvitaminD324-hydroxylase; CP24; CYP24; Cyp-24; CYP24A1; Cytochrom P450 (25-hydroxyvitamin D24-hydroxylase); cytochrome P450 24A1; cytochrome P450 family 24 subfamily A member 1; cytochrome P450, 24; cytochrome P450, 24a1; cytochrome P450, family 24, subfamily a, polypeptide 1; cytochrome P450, subfamily 24; cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase); cytochrome P450-CC24; exo-mitochondrial protein; HCAI; HCINF1; MGC126273; MGC126274; P450-CC24; vitamin D 24-hydroxylase; vitamin D(3) 24-hydroxylase; VITD12
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1591
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q07973
• Gene Symbols: Cyp24a1
• Immunogen: A synthesized peptide derived from human CYP24A1(Accession Q07973), corresponding to amino acid residues E406-G456.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG