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Invitrogen™ CYP24A1 Polyclonal Antibody
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Catalog No. PIPA5115083
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PIPA5115083 100 μL
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Catalog No. PIPA5115083 Supplier Invitrogen™ Supplier No. PA5115083
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Cytochrome P450 24A1.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP24A1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene Cyp24a1
Gene Accession No. Q07973
Gene Alias 1,25-@dihydroxyvitamin D3 24-hydroxylase; 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; 24-OHase; 24R-Ohase; 25-hydroxyvitamin D-24-hydroxylase; 25-hydroxyvitamin D3 24-hydroxylase; 25-hydroxyvitaminD324-hydroxylase; CP24; CYP24; Cyp-24; CYP24A1; Cytochrom P450 (25-hydroxyvitamin D24-hydroxylase); cytochrome P450 24A1; cytochrome P450 family 24 subfamily A member 1; cytochrome P450, 24; cytochrome P450, 24a1; cytochrome P450, family 24, subfamily a, polypeptide 1; cytochrome P450, subfamily 24; cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase); cytochrome P450-CC24; exo-mitochondrial protein; HCAI; HCINF1; MGC126273; MGC126274; P450-CC24; vitamin D 24-hydroxylase; vitamin D(3) 24-hydroxylase; VITD12
Gene Symbols Cyp24a1
Host Species Rabbit
Immunogen A synthesized peptide derived from human CYP24A1(Accession Q07973), corresponding to amino acid residues E406-G456.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1591
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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