Invitrogen™ CYP26A1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528165

Catalog No. PIPA528165

Description

Recommended positive controls: 293T, mouse liver, mouse kidney. Predicted reactivity: Mouse (96%), Rat (92%), Pig (97%), Chicken (83%), Rhesus Monkey (100%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CYP26A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues.

Specifications

• Antigen: CYP26A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CYP26A1
• Gene Alias: CP26; Cyp26; CYP26A1; Cytochrome P450 26A1; cytochrome P450 family 26 subfamily A member 1; cytochrome P450 retinoic acid-inactivating 1; cytochrome P450, 26, retinoic acid; cytochrome P450, 26, retinoic acid A1; cytochrome P450, family 26, subfamily A, polypeptide 1; cytochrome P450, subfamily XXVIA, polypeptide 1; cytochrome P450RAI; hP450RAI; P450, retinoic acid-inactivating, 1; P450RA; P450RAI; P450RAI1; RAH; Retinoic acid 4-hydroxylase; retinoic acid hydrolase; retinoic acid hydroxylase; retinoic acid-metabolizing cytochrome
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13082, 1592
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1.51 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: O43174, O55127
• Gene Symbols: CYP26A1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 246 and 497 of Human CYP26A1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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