CYP2A6 Monoclonal Antibody (OTI2A8), TrueMAB™, OriGene

Catalog No.	Quantity
50-167-4624	100 μL
50-254-0685	30 μL

Catalog No. 50-167-4624 Supplier OriGene Supplier No. TA503827

Description

Mouse Monoclonal Antibody

This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6.

Specifications

• Antigen: CYP2A6
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI2A8
• Concentration: 0.86 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: CYP2A6
• Gene Accession No.: P11509
• Gene Alias: CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB
• Gene Symbols: CYP2A6
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human CYP2A6 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1548
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b