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CYP2B6 Mouse anti-Canine, Human, Mouse, Rat, Clone: OTI3D5, lyophilized, TrueMAB™
SDP

Catalog No. 501662810
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100 μg
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50-166-2810 100 μg
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Catalog No. 50-166-2810 Supplier OriGene Supplier No. CF504328
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Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Specifications

Antigen CYP2B6
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI3D5
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene CYP2B6
Gene Accession No. P13107, P20813
Gene Alias CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450
Gene Symbols Cyp2b3, CYP2B6, Cyp2d67-ps
Host Species Mouse
Immunogen Full length human recombit protein of human CYP2B6 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100418253, 1555, 286953, 474177
Target Species Canine, Human, Mouse, Rat
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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