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Invitrogen™ CYP2B6 Polyclonal Antibody
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Catalog No. PIPA566547
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100 μL
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PIPA566547 100 μL
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Catalog No. PIPA566547 Supplier Invitrogen™ Supplier No. PA566547
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EAQCLIEELRK SKGALVDPTF LFHSITANII CSI Highest antigen sequence identity to the following orthologs - mouse 82%, rat 82%.

This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP2B6
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CYP2B6
Gene Accession No. P20813
Gene Alias 1,4-cineole 2-exo-monooxygenase; CPB6; CYP2B; CYP2B11; Cyp2b3; Cyp2b-3; CYP2B30; CYP2B6; CYP2B7; CYP2B7P; CYPIIB11; CYPIIB3; CYPIIB6; cytochrome P450 2B11; Cytochrome P450 2B3; cytochrome P450 2B6; cytochrome P450 CYP2B30; cytochrome P450 family 2 subfamily B member 6; cytochrome P-450 IIB; cytochrome P450 IIB1; Cytochrome P450 PBD-2; cytochrome P450, family 2, subfamily B, polypeptide 11; cytochrome P450, family 2, subfamily b, polypeptide 3; cytochrome P450, family 2, subfamily B, polypeptide 6; cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6; cytochrome P450IIB3; Cytochrome-P450-2B11; EFVM; IIB1; P450
Gene Symbols CYP2B6
Host Species Rabbit
Immunogen Recombinant Human CYP2B6. Recombinant protein control fragment (Product #RP-107210).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1555
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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