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Invitrogen™ CYP2C19 Polyclonal Antibody
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Catalog No. PIPA599314
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PIPA599314 100 μL
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Catalog No. PIPA599314 Supplier Invitrogen™ Supplier No. PA599314
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Cytochrome P450 2C19.

CYP2C19 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within its gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP2C19
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CYP2C19
Gene Accession No. P33261
Gene Alias (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CPCJ; CYP2C; CYP2C19; CYPIIC17; CYPIIC19; cyto; cytochrome P450 2C19; cytochrome P450 family 2 subfamily C member 19; cytochrome P-450 II C; cytochrome P450, family 2, subfamily C, polypeptide 19; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19; cytochrome P450-11A; Cytochrome P450-254C; Fenbendazole monooxygenase (4'-hydroxylating); flavoprotein-linked monooxygenase; mephenytoin 4'-hydroxylase; mephenytoin 4-hydroxylase; microsomal monooxygenase; P450-11A; P450-254C; P450C2C; P450IIC19; S-mephenytoin 4-hydroxylase; xenobiotic monooxygenase
Gene Symbols CYP2C19
Host Species Rabbit
Immunogen A synthesized peptide derived from human CYP2C19(Accession P33261), corresponding to amino acid residues E438-I488.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1557
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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