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Invitrogen™ CYP2C8 Polyclonal Antibody
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Catalog No. PIPA582491
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100 μL
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PIPA582491 100 μL
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Catalog No. PIPA582491 Supplier Invitrogen™ Supplier No. PA582491
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ICSVVFQKRF DYKDQNFLTL MKRFNENFRI LNSPWIQVCN NFPLLIDCFP GTHNKVLKNV ALTRSYIREK VKEHQASLDV NNPRDFIDCF LIKMEQEKDN QKSEFNIENL VGTVADLFVA G Highest antigen sequence indentity to the following orthologs: Mouse - 67%, Rat - 68%.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP2C8
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CYP2C8
Gene Accession No. P10632
Gene Alias CPC8; CYP2C8; CYPIIC8; Cytochrome P450 2C8; cytochrome P450 family 2 subfamily C member 8; cytochrome P450 form 1; Cytochrome P450 IIC2; cytochrome P450 MP-12; Cytochrome P450 MP-20; cytochrome P450, family 2, subfamily C, polypeptide 8; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8; flavoprotein-linked monooxygenase; microsomal monooxygenase; MP-12/MP-20; P450 form 1; P450 IIC2; P450 MP-12/MP-20; s-mephenytoin 4-hydroxylase; xenobiotic monooxygenase
Gene Symbols CYP2C8
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CYP2C8. Recombinant protein control fragment (Product #RP-90971).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1558
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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