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Invitrogen™ CYP2E1 Polyclonal Antibody
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Catalog No. PIPA552652
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100 μL
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PIPA552652 100 μL
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Catalog No. PIPA552652 Supplier Invitrogen™ Supplier No. PA552652
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EKLHEEIDRV IGPSRIPAIK DRQEMPYMDA VVHEIQRFIT LVPSNLPHEA TRDTIFRGYL IPKGTVVVPT LDSVLYDNQE FPDPEKFKPE HFLNENGKFK YSDYFKPFST GKRVCAG Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP2E1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Cyp2e1
Gene Accession No. P05181, P05182, Q05421
Gene Alias 4-nitrophenol 2-hydroxylase; CP2E1; CPE1; Cyp2e; Cyp2e1; Cyp2e-1; CYPIIE1; cytochrome P450 2E1; cytochrome P450 family 2 subfamily E member 1; cytochrome P450 subfamily 2e1 (ethanol-inducible); cytochrome P450, 2e1, ethanol inducible; cytochrome P450, family 2, subfamily e, polypeptide 1; cytochrome P450, subfamily 2E, polypeptide 1; cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1; cytochrome P450-ALC; Cytochrome P450-J; cytochrome P450RLM6; flavoprotein-linked monooxygenase; microsomal monooxygenase; P450C2E; P450-J; P450RLM6; xenobiotic monooxygenase
Gene Symbols Cyp2e1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CYP2E1. Recombinant protein control fragment (Product #RP-90208).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13106, 1571, 25086
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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