Invitrogen™ CYP2R1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5111167

Catalog No. PIPA5111167

Description

Immunogen sequence: TYEDTDFQHM IELFSENVEL AASASVFLYN AFPWIGILPF GKHQQLFRNA AVVYDFLSRL IEKASVNRKP QLPQHFVDAY LDEMDQGKND PSSTFSKENL IFSVGELIIA GTETTTNVLR.

CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in CYP2R1 gene has been associated with selective 25-hydroxyvitamin D deficiency.

Specifications

• Antigen: CYP2R1
• Classification: Polyclonal
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6VVX0
• Gene Symbols: Cyp2r1
• Immunogen: Recombinant Protein corresonding to Human CYP2R1. Recombinant protein control fragment (Product #RP-90562).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Gene: Cyp2r1
• Gene Alias: Cyp2r1; Cytochrome P450 2R1; cytochrome P450 family 2 subfamily R member 1; cytochrome P450, 2r1; cytochrome P450, family 2, R1; cytochrome P450, family 2, subfamily R, polypeptide 1; vitamin D 25-hydroxylase
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 120227
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov