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Invitrogen™ CYP2R1 Polyclonal Antibody
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Catalog No. PIPA5111167
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100 μL
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PIPA5111167 100 μL
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Catalog No. PIPA5111167 Supplier Invitrogen™ Supplier No. PA5111167
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TYEDTDFQHM IELFSENVEL AASASVFLYN AFPWIGILPF GKHQQLFRNA AVVYDFLSRL IEKASVNRKP QLPQHFVDAY LDEMDQGKND PSSTFSKENL IFSVGELIIA GTETTTNVLR Highest antigen sequence indentity to the following orthologs: Mouse - 93%, Rat - 92%.

CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in CYP2R1 gene has been associated with selective 25-hydroxyvitamin D deficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP2R1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Cyp2r1
Gene Accession No. Q6VVX0
Gene Alias Cyp2r1; Cytochrome P450 2R1; cytochrome P450 family 2 subfamily R member 1; cytochrome P450, 2r1; cytochrome P450, family 2, R1; cytochrome P450, family 2, subfamily R, polypeptide 1; vitamin D 25-hydroxylase
Gene Symbols Cyp2r1
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human CYP2R1. Recombinant protein control fragment (Product #RP-90562).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 120227
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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