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Invitrogen™ CYP2R1 Polyclonal Antibody
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Catalog No. PIPA5101313
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PIPA5101313 100 μL
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Catalog No. PIPA5101313 Supplier Invitrogen™ Supplier No. PA5101313
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Cytochrome P450 2R1.

CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in CYP2R1 gene has been associated with selective 25-hydroxyvitamin D deficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP2R1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Cyp2r1
Gene Accession No. Q6VVW9, Q6VVX0
Gene Alias Cyp2r1; Cytochrome P450 2R1; cytochrome P450 family 2 subfamily R member 1; cytochrome P450, 2r1; cytochrome P450, family 2, R1; cytochrome P450, family 2, subfamily R, polypeptide 1; vitamin D 25-hydroxylase
Gene Symbols Cyp2r1
Host Species Rabbit
Immunogen A synthesized peptide derived from human CYP2R1(Accession Q6VVX0), corresponding to amino acid residues C98-G148.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 120227, 244209
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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