Invitrogen™ CYP3A43 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530875

Catalog No. PIPA530875

Description

Recommended positive controls: 293T, A431, HeLa, HepG2. Predicted reactivity: Rhesus Monkey (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, it is unknown whether the enzyme is also involved in xenobiotic metabolism. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing of this gene results in three transcript variants encoding different isoforms.

Specifications

• Antigen: CYP3A43
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CYP3A43
• Gene Alias: CYP3A43; Cytochrome P450 3A43; cytochrome P450 family 3 subfamily A member 43; cytochrome P450, family 3, subfamily A, polypeptide 43; cytochrome P450, subfamily IIIA, polypeptide 43
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64816
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9HB55
• Gene Symbols: CYP3A43
• Immunogen: Recombinant protein fragment corresponding to a region within amino acids 33 and 248 of Human CYP3A43.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov