Invitrogen™ CYP3A7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5140177

Catalog No. PIPA5140177

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: LATHPDVQQK VQKEIDTVLP NKAPPTYD.

This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced.

Specifications

• Antigen: CYP3A7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CYP3A7
• Gene Alias: aryl hydrocarbon hydroxylase; CP37; CYP3A7; CYPIIIA7; Cytochrome P450 3A7; cytochrome P450 family 3 subfamily A member 7; cytochrome P450, family 3, subfamily A, polypeptide 7; cytochrome P450, subfamily IIIA, polypeptide 7; cytochrome P450-HFLA; flavoprotein-linked monooxygenase; microsomal monooxygenase; P-450(HFL33); P-450111A7; P450-HFLA; P450HLp2; xenobiotic monooxygenase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1551
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P24462
• Gene Symbols: CYP3A7
• Immunogen: Recombinant protein corresponding to Human CYP3A7. Recombinant protein control fragment (Product #RP-109485).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG