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Invitrogen™ Cyp46a1 Polyclonal Antibody
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Catalog No. PIPA528207
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100 μL
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Catalog No. Quantity
PIPA528207 100 μL
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Catalog No. PIPA528207 Supplier Invitrogen™ Supplier No. PA528207
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Mouse brain. Predicted reactivity: Mouse (91%), Rat (91%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cyp46a1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene CYP46A1
Gene Accession No. Q9WVK8, Q9Y6A2
Gene Alias CH24H; Cholesterol 24-hydroxylase; Cholesterol 24-monooxygenase; Cholesterol 24S-hydroxylase; cholestrol 24-hydroxylase; CP46; CYP46; CYP46A1; Cytochrome P450 46A1; cytochrome P450 family 46 subfamily A member 1; cytochrome P450, 46 (cholesterol 24-hydroxylase); cytochrome P450, 46a1 (cholesterol 24-hydroxylase); cytochrome P450, family 46, subfamily A, polypeptide 1; cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
Gene Symbols CYP46A1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human CYP46A1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10858, 13116
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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