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Invitrogen™ CYP4F11 Polyclonal Antibody
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Catalog No. PIPA5102019
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100 μL
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PIPA5102019 100 μL
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Catalog No. PIPA5102019 Supplier Invitrogen™ Supplier No. PA5102019
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Cytochrome P450 4F11.

The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP4F11 is an isoform of the cytochrome P450 4F protein and is expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. CYP4F11 contains 524 amino acid residues that share 80.0, 82.3 and 79.2% identity to CYP4F2, CYP4F3, and CYP4F8 amino acid sequences, respectively. CYP4F11 has catalytic properties towards endogenous eicosanoids as well as some clinically relevant drugs, and is able to metabolize large molecules such as erythromycin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP4F11
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CYP4F11
Gene Accession No. Q9HBI6
Gene Alias 3-hydroxy fatty acids omega-hydroxylase CYP4F11; CYP4F11; CYPIVF11; cytochrome P450 4F11; cytochrome P450 family 4 subfamily F member 11; cytochrome P450, family 4, subfamily F, polypeptide 11; cytochrome P450, subfamily IVF, polypeptide 11; Docosahexaenoic acid omega-hydroxylase; Long-chain fatty acid omega-monooxygenase; Phylloquinone omega-hydroxylase CYP4F11
Gene Symbols CYP4F11
Host Species Rabbit
Immunogen A synthesized peptide derived from human CYP4F11(Accession Q9HBI6), corresponding to amino acid residues I427-E477.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57834
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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