Invitrogen™ CYP4F11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553570

Catalog No. PIPA553570

Description

Immunogen sequence: YDNCRRLQCF PQPPKQNWFW GHQGLVTPTE EGMKTLTQLV TTYPQGFKLW LGPTFPLLIL CHPDIIRPIT SASAAVAPKD MIFYGFLKPW LGDGLLLSGG DKWSRHRRML TPAF Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 74%.

The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP4F11 is an isoform of the cytochrome P450 4F protein and is expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. CYP4F11 contains 524 amino acid residues that share 80.0, 82.3 and 79.2% identity to CYP4F2, CYP4F3, and CYP4F8 amino acid sequences, respectively. CYP4F11 has catalytic properties towards endogenous eicosanoids as well as some clinically relevant drugs, and is able to metabolize large molecules such as erythromycin.

Specifications

• Antigen: CYP4F11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CYP4F11
• Gene Alias: 3-hydroxy fatty acids omega-hydroxylase CYP4F11; CYP4F11; CYPIVF11; cytochrome P450 4F11; cytochrome P450 family 4 subfamily F member 11; cytochrome P450, family 4, subfamily F, polypeptide 11; cytochrome P450, subfamily IVF, polypeptide 11; Docosahexaenoic acid omega-hydroxylase; Long-chain fatty acid omega-monooxygenase; Phylloquinone omega-hydroxylase CYP4F11
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57834
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9HBI6
• Gene Symbols: CYP4F11
• Immunogen: Recombinant protein corresponding to Human CYP4F11. Recombinant protein control fragment (Product #RP-90473).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov