Invitrogen™ CYP4X1 Polyclonal Antibody

Catalog No.	Quantity
PIPA5101319	100 μL

Catalog No. PIPA5101319

Supplier: Invitrogen™ PA5101319

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Cytochrome P450 4X1.

Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The CYP4X1 gene product has been provisionally designated CYP4X1 pending further characterization.

Specifications

• Antigen: CYP4X1
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: CYP4X1
• Gene Accession No.: Q6A152, Q8K4D6, Q8N118
• Gene Alias: A230025G20; CP4X1; CYP_a; Cyp4a28-ps; Cyp4x1; CYPIVX1; cytochrome P450 4X1; cytochrome P450 family 4 subfamily X member 1; cytochrome P450, 4x1; cytochrome P450, family 4, subfamily X, polypeptide 1; EC 1.14.14.1; PRO4404; UNQ1929; UNQ1929/PRO4404
• Gene Symbols: CYP4X1
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human CYP4X1(Accession Q8N118), corresponding to amino acid residues V253-D303.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 246767, 260293, 81906
• Target Species: Human, Mouse, Rat, Monkey
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG