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Invitrogen™ CYP4X1 Polyclonal Antibody
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Catalog No. PIPA5101319
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PIPA5101319 100 μL
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Catalog No. PIPA5101319 Supplier Invitrogen™ Supplier No. PA5101319
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Cytochrome P450 4X1.

Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The CYP4X1 gene product has been provisionally designated CYP4X1 pending further characterization.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP4X1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CYP4X1
Gene Accession No. Q6A152, Q8K4D6, Q8N118
Gene Alias A230025G20; CP4X1; CYP_a; Cyp4a28-ps; Cyp4x1; CYPIVX1; cytochrome P450 4X1; cytochrome P450 family 4 subfamily X member 1; cytochrome P450, 4x1; cytochrome P450, family 4, subfamily X, polypeptide 1; EC 1.14.14.1; PRO4404; UNQ1929; UNQ1929/PRO4404
Gene Symbols CYP4X1
Host Species Rabbit
Immunogen A synthesized peptide derived from human CYP4X1(Accession Q8N118), corresponding to amino acid residues V253-D303.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 246767, 260293, 81906
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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