Invitrogen™ CYP4Z1/CYP4Z2P Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA567705

Catalog No. PIPA567705

Description

CYP4Z1/CYP4Z2P Polyclonal Antibody for Western Blot, IHC (P)

The cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega-hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.

Specifications

• Antigen: CYP4Z1/CYP4Z2P
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CYP4Z2P
• Gene Alias: CYP4A20; CYP4Z1; CYP4Z1/2; CYP4Z2P; CYPIVZ1; cytochrome P450 4Z1; cytochrome P450 family 4 subfamily Z member 1; cytochrome P450 family 4 subfamily Z member 2, pseudogene; cytochrome P450, family 4, subfamily Z, polypeptide 1; P450 4Z1/2; UNQ3060/PRO9882
• Host Species: Rabbit
• Purification Method: affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 163720, 199974
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q86W10, Q8N1L4
• Gene Symbols: CYP4Z1, CYP4Z2P
• Immunogen: Synthesized peptide derived from human CYP4Z1/CYP4Z2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG