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Invitrogen™ CYP4Z1/CYP4Z2P Polyclonal Antibody
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Catalog No. PIPA567705
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PIPA567705 100 μL
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Catalog No. PIPA567705 Supplier Invitrogen™ Supplier No. PA567705
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Description

Rabbit Polyclonal Antibody

CYP4Z1/CYP4Z2P Polyclonal Antibody for Western Blot, IHC (P)

The cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega-hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP4Z1/CYP4Z2P
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CYP4Z2P
Gene Accession No. Q86W10, Q8N1L4
Gene Alias CYP4A20; CYP4Z1; CYP4Z1/2; CYP4Z2P; CYPIVZ1; cytochrome P450 4Z1; cytochrome P450 family 4 subfamily Z member 1; cytochrome P450 family 4 subfamily Z member 2, pseudogene; cytochrome P450, family 4, subfamily Z, polypeptide 1; P450 4Z1/2; UNQ3060/PRO9882
Gene Symbols CYP4Z1, CYP4Z2P
Host Species Rabbit
Immunogen Synthesized peptide derived from human CYP4Z1/CYP4Z2.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 163720, 199974
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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