Invitrogen™ CYP4Z1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA515052

Catalog No. PIPA515052

Description

CYP4Z1 Polyclonal Antibody for Western Blot

The cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega-hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.

Specifications

• Antigen: CYP4Z1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CYP4Z1
• Gene Alias: CYP4A20; CYP4Z1; CYPIVZ1; cytochrome P450 4Z1; cytochrome P450 family 4 subfamily Z member 1; cytochrome P450, family 4, subfamily Z, polypeptide 1; UNQ3060/PRO9882
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 199974
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 2 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q86W10
• Gene Symbols: CYP4Z1
• Immunogen: KLH conjugated synthetic peptide between 89-118 amino acids from the N-terminal region of human CYP4Z1.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG