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Invitrogen™ CYP51A1 Polyclonal Antibody
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Catalog No. PIPA589258
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100 μL
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PIPA589258 100 μL
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Catalog No. PIPA589258 Supplier Invitrogen™ Supplier No. PA589258
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: WLLPGWLPLP SFRRRDRAHR EIKDIFYKAI QKRRQSQEKI DDILQTLLDA TYKDGRPLTD DEVAGMLIGL LLAGQHTSST TSAWMGFFLA RDKTLQKKCY LEQKTVCGEN LPPLTYDQLK DLNLLDRCIK ETLRLRPPIM IMMRMARTPQ TVAGYTIPPG HQVCVSPTVN QRLKDS Positive Samples: Cellular Location: Endoplasmic reticulum membrane, Microsome membrane.

P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies. CYP51A1 (cytochrome P450, family 51, subfamily A, polypeptide 1), also known as LDM (lanosterol 14-alpha demethylase) or cytochrome P450-14DM, is a 503 amino acid protein localized to endoplasmic reticulum membrane. CYP51A1 is an important enzyme for zymosterol and steroid biosynthesis. CYP51A1 catalyzes C14-demethylation of lanosterol, transforming lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. CYP51A1 is ubiquitously expressed, with highest levels found in liver, ovary, testis, lung, kidney and prostate.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP51A1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.34 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene CYP51A1
Gene Accession No. Q16850, Q64654, Q8K0C4
Gene Alias AI426508; CP51; CYP51; CYP51A1; CYPL1; CYPLI; Cytochrom P450 Lanosterol 14 alpha-demethylase; Cytochrome P450 51; cytochrome P450 51A1; cytochrome P450 family 51 subfamily A member 1; cytochrome P450 Lanosterol 14 alpha-demethylase; cytochrome P450, 51; cytochrome P450, 51 (lanosterol 14-alpha-demethylase); cytochrome P450, family 51; cytochrome P450, family 51, subfamily A, polypeptide 1; cytochrome P450, subfamily 51; Cytochrome P45014DM; cytochrome P450-14DM; cytochrome P450LI; Lanosterol 14-alpha demethylase; lanosterol 14-alpha-demethylase; LDM; P450 14DM; P45014DM; P450-14DM; P450L1; P450LI; RATCP14DM; Sterol 14-alpha demethylase
Gene Symbols Cyp51, CYP51A1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 245-420 of CYP51A1 (NP_0007771).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13121, 1595, 25427
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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