Invitrogen™ CYP7A1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100892

Catalog No. PIPA5100892

Description

Antibody detects endogenous levels of total Cytochrome P450 7A1.

CYP7A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body.

Specifications

• Antigen: CYP7A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cyp7a1
• Gene Alias: 24-hydroxycholesterol 7-alpha-hydroxylase; CHAP; cholesterol 7 alpha hydroxylase; cholesterol 7-alpha hydroxylase; cholesterol 7-alpha-hydroxylase; Cholesterol 7-alpha-monooxygenase; CP7A; CYP7; Cyp7a1; CYP7S1; CYPVII; cytochrome P450 (cholesterol hydroxylase 7 alpha); cytochrome P450 7A1; cytochrome P450 family 7 subfamily A member 1; cytochrome P450, 7a1; cytochrome P450, family 7, subfamily a, polypeptide 1; cytochrome P450, subfamily VIIA polypeptide 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13122, 1581, 25428
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P18125, P22680, Q64505
• Gene Symbols: Cyp7a1
• Immunogen: A synthesized peptide derived from human CYP7A1(Accession P22680), corresponding to amino acid residues K93-E143.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov