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Invitrogen™ CYP7B1 Polyclonal Antibody
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Catalog No. PIPA5101321
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100 μL
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PIPA5101321 100 μL
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Catalog No. PIPA5101321 Supplier Invitrogen™ Supplier No. PA5101321
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Cytochrome P450 7B1.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYP7B1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Cyp7b1
Gene Accession No. O75881
Gene Alias 24-hydroxycholesterol 7-alpha-hydroxylase; 25/26-hydroxycholesterol 7-alpha-hydroxylase; 25-hydroxycholesterol 7-alpha-hydroxylase; 3-hydroxysteroid 7-alpha hydroxylase; AW261589; CBAS3; CP7B; CYP7B1; Cytochrome P450 7B1; cytochrome P450 family 7 subfamily B member 1; cytochrome P450, 7b1; cytochrome P450, family 7, subfamily b, polypeptide 1; cytochrome P450, subfamily 7B, polypeptide 1; cytochrome P450, subfamily VIIB (oxysterol 7 alpha-hydroxylase), polypeptide 1; D3Ertd552e; hct-1; hippocampal transcript 1 protein; Oxysterol 7-alpha-hydroxylase; SPG5A
Gene Symbols Cyp7b1
Host Species Rabbit
Immunogen A synthesized peptide derived from human CYP7B1(Accession O75881), corresponding to amino acid residues R310-L360.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9420
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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