Invitrogen™ CYP7B1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101321

Catalog No. PIPA5101321

Description

Antibody detects endogenous levels of total Cytochrome P450 7B1.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.

Specifications

• Antigen: CYP7B1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cyp7b1
• Gene Alias: 24-hydroxycholesterol 7-alpha-hydroxylase; 25/26-hydroxycholesterol 7-alpha-hydroxylase; 25-hydroxycholesterol 7-alpha-hydroxylase; 3-hydroxysteroid 7-alpha hydroxylase; AW261589; CBAS3; CP7B; CYP7B1; Cytochrome P450 7B1; cytochrome P450 family 7 subfamily B member 1; cytochrome P450, 7b1; cytochrome P450, family 7, subfamily b, polypeptide 1; cytochrome P450, subfamily 7B, polypeptide 1; cytochrome P450, subfamily VIIB (oxysterol 7 alpha-hydroxylase), polypeptide 1; D3Ertd552e; hct-1; hippocampal transcript 1 protein; Oxysterol 7-alpha-hydroxylase; SPG5A
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9420
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O75881
• Gene Symbols: Cyp7b1
• Immunogen: A synthesized peptide derived from human CYP7B1(Accession O75881), corresponding to amino acid residues R310-L360.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov