Invitrogen™ CYP7B1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553639

Catalog No. PIPA553639

Description

Immunogen sequence: VRDEIDRLLQ STGQKKGSGF PIHLTREQLD SLICLESSIF EALRLSSYST TIRFVEEDLT LSSETGDYCV RKGDLVAIFP PVLHGDPEIF EAPEEFRYDR FIEDGKKKTT FFKRGKKLKC YLMPFGTGTS KC Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 69%.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.

Specifications

• Antigen: CYP7B1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cyp7b1
• Gene Alias: 24-hydroxycholesterol 7-alpha-hydroxylase; 25/26-hydroxycholesterol 7-alpha-hydroxylase; 25-hydroxycholesterol 7-alpha-hydroxylase; 3-hydroxysteroid 7-alpha hydroxylase; AW261589; CBAS3; CP7B; CYP7B1; Cytochrome P450 7B1; cytochrome P450 family 7 subfamily B member 1; cytochrome P450, 7b1; cytochrome P450, family 7, subfamily b, polypeptide 1; cytochrome P450, subfamily 7B, polypeptide 1; cytochrome P450, subfamily VIIB (oxysterol 7 alpha-hydroxylase), polypeptide 1; D3Ertd552e; hct-1; hippocampal transcript 1 protein; Oxysterol 7-alpha-hydroxylase; SPG5A
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9420
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O75881
• Gene Symbols: Cyp7b1
• Immunogen: Recombinant protein corresponding to Human CYP7B1. Recombinant protein control fragment (Product #RP-91048).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov