Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA522763

Invitrogen™ CYR61 Polyclonal Antibody, DyLight™ 650
GREENER_CHOICE

Catalog No. PIPA522763
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA522763 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA522763 Supplier Invitrogen™ Supplier No. PA522763
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with rat and mouse based on 88% sequence homology.

CYR61 is a secreted heparin binding protein, encoded by a growth factor inducible immediate-early gene that associates with the extracellular matrix and connective tissue. CYR61 is a member of a distinct family of angiogenic and vasculogenic regulators designated CCN proteins, which includes connective tissue growth factor (CTGF) and the mouse CYR61 homolog, Fisp12. As an angiogenic inducer, CYR61 binds to the cell surface receptor integrin alphavbeta3, where it then stimulates cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Expression of CYR61 is elevated during vessel growth, wound healing and chondrocyte differentiation. CYR61 is also detected in a wide variety of tumors as it induces tumor growth and functions as a marker of tumor progression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CYR61
Applications Immunohistochemistry (Paraffin), Neutralization, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.58 mg/mL
Conjugate DyLight 650
Formulation 50mM sodium borate with 0.05% sodium azide
Gene CCN1
Gene Accession No. O00622, P18406
Gene Alias 3CH61; AI325051; CCN family member 1; CCN1; cellular communication network factor 1; Cyr61; cysteine rich angiogenic inducer 61; cysteine rich protein 61; cysteine-rich angiogenic inducer 61; cysteine-rich heparin-binding protein 61; cysteine-rich, angiogenic inducer, 61; cysteine-rich, anigogenic inducer, 61; GIG1; IBP-10; IGF-binding protein 10; IGFBP10; IGFBP-10; insulin-like growth factor binding protein 10; insulin-like growth factor-binding protein 10; intermediate early; protein CYR61; Protein GIG1
Gene Symbols CCN1
Host Species Rabbit
Immunogen A synthetic peptide made to the human CYR61 protein sequence (between residues 150-250).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100339657, 16007, 3491
Target Species Human, Mouse, Rabbit
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.