Cyr61 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-2463	100 μL

Catalog No. 50-198-2463 Supplier Bioss Supplier No. BS1290R

Description

Rabbit Polyclonal Antibody

CYR61 is a secreted heparin binding protein, encoded by a growth factor inducible immediate-early gene that associates with the extracellular matrix and connective tissue. CYR61 is a member of a distinct family of angiogenic and vasculogenic regulators designated CCN proteins, which includes connective tissue growth factor (CTGF) and the mouse CYR61 homolog, Fisp12. As an angiogenic inducer, CYR61 binds to the cell surface receptor integrin alphavbeta3, where it then stimulates cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Expression of CYR61 is elevated during vessel growth, wound healing and chondrocyte differentiation. CYR61 is also detected in a wide variety of tumors as it induces tumor growth and functions as a marker of tumor progression.

Specifications

• Antigen: Cyr61
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: CCN1
• Gene Accession No.: O00622
• Gene Alias: 3CH61; AI325051; CCN family member 1; CCN1; Cellular communication network factor 1; Cyr61; cysteine rich angiogenic inducer 61; cysteine rich protein 61; cysteine rich protein 61-like; Cysteine-rich angiogenic inducer 61; cysteine-rich heparin-binding protein 61; cysteine-rich, angiogenic inducer, 61; cysteine-rich, anigogenic inducer, 61; GIG1; IBP-10; IGF-binding protein 10; Igfbp10; IGFBP-10; insulin-like growth factor binding protein 10; Insulin-like growth factor-binding protein 10; intermediate early; LOC100339657; Protein CYR61; Protein GIG1
• Gene Symbols: CCN1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human Cyr61.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3491
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG